Article about LOQ

Just got Imputing defensible values for left-censored ‘below level of quantitation’ (LoQ) biomarker measurements forwarded. It starts as interesting read stating the problem but IMHO ultimatively fails to address the problem. I am especially disappointed that neither the IUPAC definition and guidelines are mentioned, nor the current ISO 11843. Especially the works of Lloyd A. Currie offer great insight in this topic.

The whole idea of censoring values below LOQ was already debunked by Currie. While I find the whole censored data method is promising I expect it useful for cases where the measurement device reaches its limits - not cases of manual censorship.